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Project Title: Plasmodium falciparum sporozoite vaccine in Equatorial Guinean Adults

Project Description: to Evaluate the Safety, Tolerability and Immunogenicity of a Radiation-attenuated Plasmodium falciparum (Pf) Sporozoite Vaccine (PfSPZ Vaccine) in Equatoguinean Adults, Children and Infants, and Comparison with Non-attenuated Pf Sporozoites (PfSPZ Challenge) Administered under Chloroquine Prophylaxis (PfSPZ-CVac Approach) for Efficacy against Controlled Human Malaria Infection (CHMI) to Evaluate the Safety, Tolerability and Immunogenicity of a Radiation-attenuated Plasmodium falciparum (Pf) Sporozoite Vaccine (PfSPZ Vaccine) in Equatoguinean Adults, Children and Infants, and Comparison with Non-attenuated Pf Sporozoites (PfSPZ Challenge) Administered under Chloroquine Prophylaxis (PfSPZ-CVac Approach) for Efficacy against Controlled Human Malaria Infection (CHMI)


Principal Investigator : Salim Abdulla

Department Name : EHES

Time frame: (2013-06-01) - (2021-12-31)

Funding Partners
Medical Care Development International (MCDI) (Normal)
External Collaborating Partners
None added yet.